Businesses in Murphysboro, Illinois

471 local businesses across 88 categories. 0.1% of everything listed in Illinois.

Quick answer

Murphysboro, IL has 471 businesses listed on USA Business Search in 88 categories across 1 ZIP code. The most-listed are churches & places of worship, nonprofits & community, auto repair.

Updated October 2026

Most listed in Murphysboro

Churches & places of worship Nonprofits & community Auto repair Schools & tutoring General contractors Bars & breweries Restaurants Real estate agents Insurance agents Hair salons

Home services

General contractors (16)HVAC & heating (9)Plumbers (5)Movers & hauling (4)Locksmiths (3)Flooring (2)Landscaping & lawn care (2)Electricians (2)Kitchen & bath remodeling (1)Handyman services (1)Roofers (1)House cleaning (1)

Marketing & advertising

Printing & signs (5)Graphic design (2)Marketing agencies (2)Photographers & video (1)

Auto

Auto repair (18)Gas stations (6)Car dealers (5)Auto parts (4)Auto body & collision (4)Car wash & detailing (4)Tires (3)

Food & drink

Bars & breweries (16)Restaurants (13)Bakeries & desserts (8)Pizza (7)Mexican restaurants (5)Grocery & specialty food (5)Coffee shops & cafes (4)Catering (2)

Health & medical

Doctors & clinics (8)Chiropractors (5)Senior living & home care (4)Urgent care & hospitals (4)Dentists (2)Eye care (2)Pharmacies (1)Massage therapy (1)

Beauty & personal care

Hair salons (12)Spas & med spas (6)Nail salons (3)Dry cleaning & laundry (2)Barbers (2)Tattoo & piercing (1)

Professional services

Business consulting (10)Accountants & tax (4)Funeral homes (3)IT & computer services (3)Engineering & architecture (2)Shipping & couriers (1)

Real estate

Real estate agents (13)Self storage (8)Property management (3)

Finance & insurance

Insurance agents (12)Banks & credit unions (6)Financial advisors (6)

Legal

Lawyers (11)

Shopping & retail

Florists & gifts (8)Furniture & home decor (4)Thrift & consignment (4)Hardware & garden (2)Phones & electronics (2)Sporting goods & outdoor (2)Liquor stores (1)Clothing & boutiques (1)

Pets

Pet grooming & training (7)Veterinarians (6)Pet stores (1)

Fitness & recreation

Gyms & fitness (8)Dance studios (2)Yoga studios (1)Golf (1)Martial arts (1)

Hotels & travel

Hotels & lodging (11)Vacation rentals (7)Travel agencies (3)Campgrounds & RV parks (1)

Education & childcare

Schools & tutoring (17)Childcare & preschools (1)

Events & entertainment

Arts & entertainment (10)Event venues (2)Event planning & weddings (1)

Business & industrial

Manufacturing & wholesale (7)Farms & agriculture (5)Propane & energy (5)

Community & faith

Churches & places of worship (35)Nonprofits & community (19)

More businesses in Murphysboro

Auto parts (4)

Fisher Auto Parts

202 Blair St, Murphysboro, IL 62966 · Claim or fix

Call (618) 565-2530 Website

NAPA Auto Parts

860 W Industrial Park Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 565-2200 Website

O'Reilly Auto Parts

202 N Williams St, Murphysboro, IL 62966 · Claim or fix

Call (618) 565-1771 Website

PLP Battery Supply

1362 N 7th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-3344 Website

Coffee shops & cafes (4)

Cold Blooded Coffee & Roastery

1318 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 471-4112 Website

I AM Java Coffee House

715 N 14th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 534-5341 Website

Leisure 73

6 IL-4, Murphysboro, IL 62966 · Claim or fix

Call (907) 267-1255

Rich GO

1041 3rd Ave S, Murphysboro, IL 62966 · Claim or fix

Call (206) 463-5310

Movers & hauling (4)

Bost Truck Service

1134 N 11th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-3166 Website

U-Haul Neighborhood Dealer

550 E Industrial Park Rd Bldg 15, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-4288 Website

U-Haul Neighborhood Dealer

10519 Highway 149, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-4288 Website

U-Haul Neighborhood Dealer

1134 N 11th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 565-0381 Website

Furniture & home decor (4)

Aaron's Rent To Own

60 Niemann Ln, Murphysboro, IL 62966 · Claim or fix

Call (618) 565-1100 Website

George's Resale

1324 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-1337 Website

Gillenberg Furniture & Appliances

901 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-6031

BoxDrop Mattress and Furniture

1320 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 777-6763

Auto body & collision (4)

Grither Paint and Body

383 Amusement Pk Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-4545 Website

Christopher R Grither

100 E New Hill Dr, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-4545 Website

Stewart's Body Shop

215 N 9th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-2011 Website

Jimmy's Auto and Body Shop

109 Reichrath Dr, Murphysboro, IL 62966 · Claim or fix

Call (618) 521-7001

Senior living & home care (4)

Our Place

301 N 13th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-1415 Website

Big Muddy River Assisted

5 N Shawnee Dr, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-5818 Website

River To River Residential

5 E Shawnee Dr, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-5002 Website

River to River Residential Corporation

5 N Shawnee Dr, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-5002 Website

Car wash & detailing (4)

Allied Automotive Brokers & Detailing

2040 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-2886 Website

Murphy Pride Car Wash

802 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 615-5061 Website

Whistle Clean Car Wash Center

1834 Walnut St #1908, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-4577 Website

Shelton's Truck Wash

1248 Enterprise Ave, Murphysboro, IL 62966 · Claim or fix

Call (618) 534-3973

Accountants & tax (4)

Koberstein Clarke

104 N 14th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-2334 Website

Morgan Donald R Cpa

217 Robert Morgan Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-3762 Website

H&R Block

1404 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-1531

Ayres Accounting

250 S 9th St, Murphysboro, IL 62966 · Claim or fix

Call (314) 375-6444

Thrift & consignment (4)

Think Vintage

1338 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 521-8610 Website

Jenette’s Resale

2142 Logan St, Murphysboro, IL 62966 · Claim or fix

Call (618) 565-5127

Nance's Trading Post

2254 IL-13 BUS, Murphysboro, IL 62966 · Claim or fix

Call (618) 713-6511

Faith & Family Thrift Store

1416 Walnut St, Murphysboro, IL 62966 · Claim or fix

Website

Urgent care & hospitals (4)

St Joseph Memorial Hospital

2 S Hospital Dr, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-3156 Website

Jackson County Ambulance Headquarters

10169 Old Highway 13, Murphysboro, IL 62966 · Claim or fix

Call (618) 529-5158 Website

ARCH Air Medical Service- Carbondale, IL Base

430 Airport Rd, Murphysboro, IL 62966 · Claim or fix

Call (800) 325-9191 Website

Jackson County Ambulance

1001 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-5524 Website

Tires (3)

Plaza Tire Service

801 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-4525 Website

All Hours Auto Repair

141 Ruth Ln, Murphysboro, IL 62966 · Claim or fix

Call (618) 669-0454 Website

Plaza Tire Service

1801 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-4525

Nail salons (3)

Art Of Hair

1017 N 14th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-4747 Website

Bally's Nails Spa

1836 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 967-4987

Sky Nails

550 E Industrial Park Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 565-5010

Locksmiths (3)

Minute Key

6495 Country Club Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 319-2651 Website

KeyMe Locksmiths

550 E Industrial Park Rd Ste 11, Murphysboro, IL 62966 · Claim or fix

Call (618) 777-5610 Website

Express Towing

199 Wells St, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-6563

Funeral homes (3)

Crain Funeral Home and Cremation Service

31 Memorial Dr, Murphysboro, IL 62966 · Claim or fix

Call (866) 592-7246 Website

Crawshaw Funeral Home

1421 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (866) 592-7246 Website

Pleasant Grove Cemetary

31 Memorial Dr, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-1145 Website

Travel agencies (3)

Rendleman Aviation LLC

57 Watt Hill Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 534-8035 Website

Southern Illinois Historic Preservation

1515 Oak St, Murphysboro, IL 62966 · Claim or fix

Call (618) 201-7435 Website

Thunderbird Travel

601 Walnut St Ste 200, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-2100

IT & computer services (3)

B & J Computers

1032 W Industrial Park Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-4459 Website

Egghead Computers

430 N 11th St Apt 5, Murphysboro, IL 62966 · Claim or fix

Call (618) 203-5380 Website

Care Trak

1202 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (800) 842-4537 Website

Property management (3)

GreenRetreat LLC.

6096 Chautauqua Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-1717 Website

Premier Property Management And Development

347 S Williams St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-3900 Website

Rsg Properties

89 Goldenwood Ln, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-6755 Website

Flooring (2)

Niemann's American Flooring and Benjamin Moore Paint

138 Niemann Ln, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-2231 Website

Southern Illinois Epoxy

374 S Williams St, Murphysboro, IL 62966 · Claim or fix

Call (618) 228-3864 Website

Landscaping & lawn care (2)

Murphysboro Lawn & Garden

902 N 14th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 967-7047 Website

Schuman's Landscaping

762 Maes Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 525-5255 Website

Graphic design (2)

Spectrum Graphics

184 Marina Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 924-5895 Website

Distinctive Flooring

10543 Highway 149, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-5320 Website

Hardware & garden (2)

R.p. Lumber

22 Lumber Ln, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-3188 Website

Yates Awning LLC.

1050 Airport Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 529-4808

Marketing agencies (2)

Crimson Creative

1416 Walnut St Ste b, Murphysboro, IL 62966 · Claim or fix

Call (618) 614-0335 Website

Idea Creative Marketing

1214 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 529-0969 Website

Dance studios (2)

The Dance Barre Southern Illinois

1418 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (979) 229-9553 Website

Studio 84

1418 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 201-7952

Event venues (2)

Moose Lodge Murphysboro

9663 Old Highway 13, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-3232 Website

Davis-McCann Civic Center

1410 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-1142 Website

Engineering & architecture (2)

Midwest Reclamation Resources

1023 N 14th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-5590 Website

Premier Architecture Design And Build, Llc

347 S Williams St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-3900 Website

Dentists (2)

Durr Michael R DMD

864 Koonce Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 457-7243 Website

Murphysboro Smile Design

217 Robert Morgan Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-3737 Website

Eye care (2)

Marion Eye Center

1934 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 565-1406 Website

Spears Vision Center

1008 Locust St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-2922

Electricians (2)

B W Electric & Locating LLC

9704 Highway 127, Murphysboro, IL 62966 · Claim or fix

Call (618) 534-5221 Website

Murphysboro Electric

916 W Industrial Park Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-3392

Catering (2)

One Hot Cookie Bakery and Catering

1290 Business Highway 13, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-1444 Website

Heartland Catering Inc.

4404 Chautauqua Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-4094 Website

Phones & electronics (2)

Rent One

550 E Industrial Park Rd Ste 8, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-8266 Website

Verizon Wireless

6495 Country Club Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-5041

Dry cleaning & laundry (2)

14th Street Laundromat

715 N 14th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 534-4532

Able Cleaners & Furriers

101 S 16th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-4511

Sporting goods & outdoor (2)

Southern Illinois Sports Resale

601 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-2565 Website

Broadheads Over Bullets Archery

5369 Country Club Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 967-2490

Barbers (2)

Joe's Barber Shop

1903 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-3288 Website

HairReplacement Clinic & Barbershop

1883 Business Highway 13, Murphysboro, IL 62966 · Claim or fix

Call (618) 303-7068

Kitchen & bath remodeling (1)

CAPITAL SUPPLY CO

220 S 13th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-3196

Childcare & preschools (1)

Kid's Day Out

938 Keough Dr, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-5463

Handyman services (1)

Gillenberg Sales & Service

2006 Elm St, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-6031 Website

Yoga studios (1)

Yoga on the Block of Murphysboro, IL

1330 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 708-2901 Website

Liquor stores (1)

Southern Illinois Liquor Mart

113 N 12th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-4727 Website

Roofers (1)

Clover Roofing

153 Seeker Hill Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-4824 Website

Pharmacies (1)

Walgreens

503 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 565-2329 Website

Massage therapy (1)

B/b Massage & Sports Training

1017 N 14th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 519-0698

House cleaning (1)

Start

20 N 13th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-2378 Website

Golf (1)

Jackson County Country Club

5776 Country Club Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-2387 Website

Photographers & video (1)

Whimsey Photography

5 N 15th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-2333 Website

Tattoo & piercing (1)

Artistic Mind Tattoos

104 N 10th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-5184

Shipping & couriers (1)

UPS Authorized Shipping Provider

208 S Williams St, Murphysboro, IL 62966 · Claim or fix

Call (618) 687-1702 Website

Clothing & boutiques (1)

Tibby Knoll Boutique and Vintage Home Goods

418 N 14th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 201-5000 Website

Campgrounds & RV parks (1)

Dry Lake Campground

43 Dry Lake Rd, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-8486 Website

Martial arts (1)

Murphysboro Moo Sul Kwan Martial

220 N 11th St, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-5611

Event planning & weddings (1)

Murphysboro Event Center

1329 Walnut St, Murphysboro, IL 62966 · Claim or fix

Call (618) 305-0078 Website

Pet stores (1)

Quality Cove

1 Apple City Ctr, Murphysboro, IL 62966 · Claim or fix

Call (618) 684-5900 Website

Common questions

How many businesses are listed in Murphysboro, Illinois?

USA Business Search lists 471 businesses in Murphysboro across 88 categories. The most-listed are churches & places of worship, nonprofits & community, auto repair.

Which ZIP codes does Murphysboro cover?

Listings include ZIP codes 62966.

How do I check that a Murphysboro business is legitimate?

Search the state's business registry and licensing boards. Our Illinois business lookup guide links each official search.

How do I add my business?

It's free: use Add your business. Owners can also claim and fix an existing listing.

Other Illinois cities

Chicago Naperville Rockford Springfield Schaumburg Peoria Aurora Joliet All Illinois cities

Own a business in Murphysboro? Add it free or claim your listing.