Businesses in Sikeston, Missouri
965 local businesses across 94 categories. 0.5% of everything listed in Missouri.
Sponsored
Quick answer
Sikeston, MO has 965 businesses listed on USA Business Search in 94 categories across 2 ZIP codes. The most-listed are churches & places of worship, nonprofits & community, restaurants.
Updated October 2026Most listed in Sikeston
Churches & places of worshipNonprofits & communityRestaurantsBusiness consultingCar dealersSenior living & home careAuto repairInsurance agentsClothing & boutiquesDoctors & clinics
Home services
Marketing & advertising
Auto
Food & drink
Health & medical
Beauty & personal care
Professional services
Real estate
Finance & insurance
Legal
Shopping & retail
Pets
Fitness & recreation
Hotels & travel
Education & childcare
Events & entertainment
Business & industrial
Community & faith
More businesses in Sikeston
Bars & breweries (4)
Cheers Bar & Grill
The Copper Still Lounge
Friend's Bar & Grill
Travel agencies (4)
Harper's Travel Service
Hertz
Sikeston Tourism
I-55 N
Pet stores (4)
Petsense by Tractor Supply
Critter Stuff
HeeHaw Supply
Quick-Tag
Shipping & couriers (4)
The UPS Store
United States Postal Service
UPS Access Point location
UPS Customer Center
Physical therapy (4)
Health Facilities Rehab Services
ReStart Rehabilitation Services
Sovereign Healthcare Group
Sikeston Rehab Llc
Event planning & weddings (4)
Center Street Station
Five Star Inflatables
Heartland Supported Living
Arcade Party
Wellness & alternative health (3)
Avant-guarde Healthcare
Hydration Haven LLC
Scott County Wic
Massage therapy (3)
Kate's Therapeutic Touch
Semo Massage Therapy
Antonio's
Tattoo & piercing (3)
True Hand Tattoo
J.A.B.Man Piercings
Monster Tattoo Studio
Staffing & employment (3)
Express Employment Professionals
Manpower
Professional Development Services
Software development (3)
Catering (3)
Trisha's BBQ and Catering
Personal Touch Caterings & Events
Dirty Fizz Sikeston
Campgrounds & RV parks (3)
Town & Country Camping & Storage
Hinton Park Inc RV Park
Cypress Creek RV Park
Landscaping & lawn care (2)
Murdock excavation and tree service
C & J Tree And Lawn Service
Electricians (2)
Chelsea Electric Co.
One Source Electric
Jewelry (2)
Sam's Fine Jewelry
The Gold Buying Center of Sikeston Inc.
Martial arts (2)
Missouri Taekwondo Institute
Sikeston BJJ
IT & computer services (2)
Mobile Tech Computer Services
Wizards PC and Phone Repair Service
Property management (2)
Collom Rentals and J&E Rentals of Sikeston Missouri
Stewart Rentals
Golf (2)
Bootheel Golf Club
The Bunker Golf 365, LLC
Flooring (2)
Carpet Direct
Ultimate Flooring & Finishes
Graphic design (1)
Seraphic Design
Cannabis dispensaries (1)
Greenlight Dispensary Sikeston
Dance studios (1)
Melissa's Studio-Performing
Engineering & architecture (1)
Waters Engineering
Dry cleaning & laundry (1)
Southern Suds
Plumbers (1)
N J Werner Heating Plumbing & Air
Auto glass (1)
All Tint
Windows & doors (1)
Maverick Glass Shop
Advertising agencies (1)
Unilever Ice Cream Plant
Handyman services (1)
GSB Services
Common questions
How many businesses are listed in Sikeston, Missouri?
USA Business Search lists 965 businesses in Sikeston across 94 categories. The most-listed are churches & places of worship, nonprofits & community, restaurants.
Which ZIP codes does Sikeston cover?
Listings include ZIP codes 63801, 03301.
How do I check that a Sikeston business is legitimate?
Search the state's business registry and licensing boards. Our Missouri business lookup guide links each official search.
How do I add my business?
It's free: use Add your business. Owners can also claim and fix an existing listing.
Other Missouri cities
Own a business in Sikeston? Add it free or claim your listing.